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Mutated ATXN3 activates CHEK2. 1 / 1

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"Furthermore, to test whether mutant ATXN3 activates p53 and Chk2 via activating ATM, we pre-treated the cells with ATM inhibitor Ku55933 and expressed ATXN3-Q84 and assessed the activation of DNA damage response pathway."

25590633

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Mutated ATXN3 activates CHEK2. 1 / 1

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