IndraLab

Statements

ARR3 binds USP33. 5 / 6
1 | 5
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"Akt facilitates the interaction between USP33 and arrestin3."
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"Immunocytochemical analysis showed that USP33 formed a complex with arrestin3 under desensitization conditions (Fig. 3D; Quin, w +)."
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"As shown in Fig. 3A and B, interactions between USP33, D R, and arrestin3 remained similar under non-desensitization conditions (30 nM DA, w +), but increased under desensitization conditions (100 nM Quin, w +)."
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"In addition, an interaction between USP33 and arrestin3 occurred in an Mdm2-dependent manner (Fig. 3C)."
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"Consistent with the inhibition of arrestin3 deubiquitination by pretreatment with triciribine (Fig. 5B), this pretreatment was found to block the interaction between arrestin3 and USP33 (Fig. 6E)."
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