IndraLab

Statements

USP20 inhibits cell population proliferation. 5 / 5
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"Silencing of USP20 increases proliferation in GC cells."
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"In HTLV-1-transformed cells, the transcription of USP20 is reduced compared with HTLV-1-negative T cells, and ectopic USP20 expression was found to inhibit the proliferation of an HTLV-1-transformed cell line, MT4."
| PMC
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"In line with the clinical outcomes, we found that the overexpression of USP20 could, on one hand, suppress cell proliferation and delay G1-S cell cycle transition, and on the other hand, enhance autophagy in GC cells."
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"Since overexpression of USP20 inhibits the proliferation of ATL cells, it raises the possibility that induction of USP20 could be used to inhibit HTLV induced oncogenesis."
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"Experimentally, small interfering RNA mediated knockdown of USP20 expression significantly promoted cell proliferation, accelerated G1-S phase transition and attenuated the autophagy activity."
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