IndraLab

Statements


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"The knockdown of the deubiquitinating enzyme USP4 (ubiquitin specific peptidase 4) reduced the numbers of P-bodies, adding further evidence for ubiquitin chains as critical regulators of P-bodies [195]."

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"USP4 promotes the activation of Rheb by removing ubiquitin from it."

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"Like other USPs, USP4 also mediates the removal and processing of ubiquitin."

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"USP4 DUSP-Ubl promotes ubiquitin release."

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"The DUSP-Ubl domain of USP4 enhances its catalytic efficiency by promoting ubiquitin exchange."

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"Pulse-chase analysis of Y-betagal degradation in yeast revealed that Y-betagal is degraded at wild-type rates when Unp is expressed (results not shown), consistent with the ONPG assay and reinforcing [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"