IndraLab

Statements

CNR2 inhibits USP4. 5 / 5
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"Additionally, it has been reported that CB2 inhibited USP4, leading to the stabilization of TGF-β1R, and subsequently ameliorating hepatic autoimmune hepatitis (74)."
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"Liver X Receptor alpha-Induced Cannabinoid Receptor 2 Inhibits Ubiquitin-Specific Peptidase 4 Through miR-27b, Protecting Hepatocytes From TGF-beta."
31592043
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"Conclusion: LXRalpha exerts a cytoprotective effect against TGF-beta by transcriptionally regulating the CB2 gene in hepatocytes, and CB2 then inhibits USP4-stabilizing TbetaRI through miR-27b."
31592043
sparser
"Additionally, it has been reported that CB2 inhibited USP4, leading to the stabilization of TGF-β1R, and subsequently ameliorating hepatic autoimmune hepatitis ( xref )."
38322269
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"Thus, LXRalpha could exert a protective effect against TGF-beta by transcriptional regulation of the CB2R gene in hepatocytes, and then CB2 might inhibit USP4 stabilizing TbetaRI via miR-27b."
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