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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CNR2 inhibits USP4. 2 / 2

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"Conclusion : LXRalpha exerts a cytoprotective effect against TGF-beta by transcriptionally regulating the CB2 gene in hepatocytes, and CB2 then inhibits USP4 stabilizing TbetaRI through miR-27b."

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"Thus, LXRalpha could exert a protective effect against TGF-beta by transcriptional regulation of the CB2R gene in hepatocytes, and then CB2 might inhibit USP4 stabilizing TbetaRI via miR-27b."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...