IndraLab

Statements


Doxazosin decreases the amount of KCNH2. 2 / 2
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"The data imply that doxazosin related reduction of hERG protein expression may be linked to increased apoptosis rates."

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"Consistent with this notion, terazosin (100 microM; 24 h) exhibited weak effects on hERG protein levels in LNT-229 cells (-20.4 +/-2.8%; n = 3; p = 0.03), while doxazosin (30 microM; 24 h) suppressed hERG expression by 48.2 +/-1.7% (n = 3; p = 0.002; XREF_FIG)."