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UCHL3 leads to the ubiquitination of Ku. 1 / 1

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"Lastly, we provide evidence showing that DNA damage-induced UCHL3 phosphorylation (which is dependent on UCHL3 catalytic activity, ATM kinase and downstream NHEJ factors) promotes destabilization of UCHL3, suggesting that UCHL3 may dissociate from Ku80 to allow Ku ubiquitylation and subsequent removal from DNA."

30559450

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IndraLab

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UCHL3 leads to the ubiquitination of Ku. 1 / 1

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