IndraLab

Statements

U0126 inhibits NLRP3. 6 / 6
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"By inhibiting ERK and NF-kappaB, U0126 and BAY 117082 inhibited mir-21 over-expression-induced activation of the NLRP3 inflammasome complex."
29084974
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"Moreover, we found that the overexpression of miR-155 promoted the activation of the ox-LDL-induced NLRP3 inflammasome, which could also be blocked by the ERK inhibitor U0126."
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"TEA, U0126, and INF39 all inhibited NLRP3, caspase-1 activation, and Il-1β maturation (Figure 7A,B)."
31191310
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"By inhibiting ERK and NF-κB, U0126 and BAY 117082 inhibited mir-21 over-expression-induced activation of the NLRP3 inflammasome complex."
29084974
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"U0126 or BAY, inhibitor of ERK or NF-kappaB, inhibited activation of NLRP3 inflammasome complex induced by mir-21 overexpression."
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"In shScr BMDMs, LPS priming increased mitochondrial distribution of NLRP3, which is inhibited by U0126 (XREF_FIG)."
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