IndraLab

Statements

USP28 activates apoptotic process. 11 / 11
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"Remarkably, both apoptosis and microcephaly were rescued by the removal of 53bp1, Usp28 or p53 in Sas‐4 conditional mutants [69, 141]."
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"Moreover, the upregulation of CCND1 and USP28 partially reverses the impaired proliferation and promoted apoptosis rate induced by miR-3940-5p in A549 cells (XREF_FIG, E-H)."
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"Downregulation of CCND1 and USP28 Inhibits Proliferation and Induces Apoptosis in A549 Cells."
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"Down-regulation of USP28 induced cell apoptosis."
25656529
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"Commentary on: Rovsing et al. Resistance to vincristine in DLBCL by disruption of p53-induced cell cycle arrest and apoptosis mediated by KIF18B and USP28."
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"Down-regulation of USP28 promoted NSCLC cells proliferation and induced cells apoptosis."
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"Moreover, FACS apoptosis analysis indicated that down-regulation of USP28 expression by siRNA increased the NSCLC cells apoptosis rate."
25656529
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"LncRNA-SNHG14/miRNA-3940-5p/NAP12 mRNA may be potential for CRC diagnosis and prognosis.8 miR-3940-5p negatively regulates CUL7 and activates NF-κB to promote gliomagenesis in human gliomas.38 miR-3940-5p targets CCND1 and USP28 to inhibit proliferation and induce apoptosis in NSCLC cells."
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"Resistance to vincristine in DLBCL by disruption of p53-induced cell cycle arrest and apoptosis mediated by KIF18B and USP28."
37190875
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"Hence, silencing of USP28 antagonized apoptosis induced by caspase-8 depletion and also reverted accumulation and activation of p53 (XREF_FIG)."
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"USP28 has a crucial role in regulating Chk2-p53-PUMA signaling pathways and is involved in DNA damage-induced apoptosis in response to double-strand breaks [63,64] ."
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