IndraLab

Statements

DAB1 activates HCN1. 4 / 4
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"Loss of Reelin or Dab1 Drastically Reduces HCN1 Localization in the Distal Dendrites."
25201528
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"We found that Dab1 knockdown in adult mice drastically reduced distal dendritic HCN1 in the hippocampal CA1 region (XREF_FIG), whereas MAP2 levels were unchanged (XREF_FIG), demonstrating the importance of Reelin signaling throughout postnatal life."
25201528
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"However, our data do not support this hypothesis, because inhibiting Reelin signaling using GST-RAP in concentrations that lower Dab1 phosphorylation to 72% of controls did not markedly reduce the distal dendritic HCN1 enrichment that was observed after E2 treatment."
30406178
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"Loss of Dab1 greatly reduced HCN1 staining in L1, compared with HCN1 expression in the control (contralateral) hemisphere (XREF_FIG)."
25201528