IndraLab

Statements

TNF binds NOTCH1. 16 / 16
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"JAM2–JAM3, C5AR1–RPS19, TNF–DAG1 and TNF–NOTCH1 signaling pathways are associated with OL maturation and myelination."
37697166
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"We also observed potential interacting pairs between EP_C1_LMP1 cells with activated Notch pathway and multiple cell types through NOTCH1-TNF and NOTCH2-JAG2, which have been related to radiation sensitivity xref and cancer stem-like side population cells xref in NPC (Supplementary Fig.  xref )."
33531485
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"Interestingly, 14 pairs of ligand-receptor pairs were specifically associated with E12 and E18, among which the TNF-NOTCH1 ligand-receptor pair was significantly enriched (Fig.  xref B)."
41455767
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"We observed that, some classical signaling such as TNF-NOTCH1 pair was expressed in all eight gained ImC-LSC, as reported, Notch and TNF signaling had all been verified to regulate the homeostasis of the corneal epithelium and the corneal inflammatory response and wound healing after injury [ xref – xref ]."
38971839
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"Next, we found that non-HBV T/NK cells had the strongest proinflammatory cytokine interactions with myeloid clusters via the IFNG-IFNGR1, TNF-TNFRSF1B, TNF-VSIR, TNF-TNFRSF1A, TNF-NOTCH1, and TNF-SEMA4C axes, suggesting that IFNG and TNF activated myeloid cells xref (Fig.  xref )."
40634523
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"For the receptor-ligand interaction, Agrafioti et al. [ xref ] found that PVR-TIGIT, PVR-CD96, and PV-CD226 receptor/ligand pairs interact between M1 and T cells, while TNF-NOTCH1 and PVR-TNFSF9 receptor/ligand pairs interact between M1 and B cells, and many other cross-talks were enhanced in periodontitis-affected sites."
40058341
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"TNF promoted p52/RELB binding to NICD, which enhanced binding at the RBPjκ site within the Hes1 promoter."
24892805
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"By linking Notch and TNFalpha it was shown that (1) Notch-1 mucosal expression differs in inflamed and non inflamed mucosa and increases in response to anti-TNFalpha treatment; (2) Notch-1 function is regulated by TNFalpha inhibitors; (3) Notch-1 binds to TNFalpha; and (4) Notch-1 inhibition prevents anti-TNFalpha-induced T cell cycle arrest but not apoptosis."
22068169
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"In addition, the CellphoneDB analysis and coculture experiments revealed the potential mechanism of the TNF-NOTCH1 signaling axis in microglia and Müller cells, including their functional clusters."
41455767
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"By linking Notch and TNFα it was shown that (1) Notch-1 mucosal expression differs in inflamed and non-inflamed mucosa and increases in response to anti-TNFα treatment; (2) Notch-1 function is regulated by TNFα inhibitors; (3) Notch-1 binds to TNFα; and (4) Notch-1 inhibition prevents anti-TNFα-induced T cell cycle arrest but not apoptosis."
22068169
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"In addition, the interaction of NOTCH1-TNF, TGFB1-TGFβ receptor and CD47-SIRPA were also found between malignant T cells and LAMP3 + cDCs ( Fig. 5 F)."
36265653
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"CellphoneDB analysis revealed that the ligands (WNT5A, PDGFB, IGF1, PROS1, OSM, and TNF) were specifically expressed in MES-MDM 1 and 2 ( xref A and B) and suggested an enhanced interaction of TNF-CELSR2, TNF-PTPRS, TNF-DAG1, TNF-SEMA4C, TNF-NOTCH1, TNF- RIPK1 between MES-MDM and MES/NPC-like cancer cells ( xref G and xref C)."
40373963
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"Microglial aging intrinsically disrupts the oligodendrocyte signaling pathways (e.g., JAM2-JAM3, TNF-NOTCH1), contributing to myelin deficits and cognitive impairment [ xref ]."
40943076
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"LAMP3+ cDC cells were enriched in CTCL, with notable interactions of TGFB1-TGFβ, NOTCH1-TNF, CD47-SIRPA between cDCs and malignant T cells [ xref ]."
40941016
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"The upregulation of constitutive nuclear factor NF-κB, as well as CD30, CD40, tumor necrosis factor (TNF)-α, and Notch1 interactions contributes to these processes ( xref )."
26498453
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"In parallel with our findings, Daniel et al. [43] reported that TNF-α inhibited Mfn2 expression in cells and that Notch1 could directly bind to TNF-α [44] , supporting positive regulation of Mfn2[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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