IndraLab

Statements

Baicalein inhibits MYD88. 6 / 6
| 6
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"Baicalein attenuated inflammatory cell infiltration, alveolar wall edema, decreased W/D ratio and levels of TLR4, MyD88, and TRIF in the lung tissues, reduced levels of inflammatory factors in pancreatic and lung tissues and BALF, diminished ROS, and elevated GSH, SOD and CAT in pancreatic and lung tissues of SAP-ALI rats."
38557861
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"Baicalein decreased the activation of TLR4 and MyD88 signaling molecules."
29180692
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"Baicalein, one of the active ingredients of Scutellariae Radix for UC, can block the TLR4/MyD88 signaling pathway, upregulate TGF-β content, enhance the protective barrier of the intestine, and alleviate the symptoms of UC."
38501018
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"The TLR4/MyD88 signaling cascades (NF-κB and MAPK) in lipopolysaccharide (LPS)-stimulated macrophages were downregulated by baicalein."
37849728
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"In vitro, baicalein suppressed the TLR4/MyD88 signal cascades (NF-κB and MAPKs) in LPS-activated macrophages."
37324477
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"In this study, we showed that baicalein significantly inhibited the up-regulation of TLR4 and MyD88 in TNBS induced colitis mice and in LPS induced macrophages."
29180692