IndraLab

Statements

USP25 activates Neoplasm Invasiveness. 30 / 30
| 30
reach
"Our data revealed that knockdown of USP21 markedly reduced invasiveness of 786-O."
27259257
reach
"Plate formation and transwell assays revealed that USP21 -induced enhancement of cell growth, migration, and invasion in KYSE-150 and Eca-109 cells was obviously abolished by G3BP1 depletion (Fig. 4B–D, Fig. S8B–D)."
38906857
reach
"Taken together, these studies suggest that USP21 plays an important role in the development of HCC.Moreover, USP21 promotes the migration and invasion of colorectal cancer by acting as a DUB for Fos-related-antigen-1 (Fra-1), a transcription factor essential for cancer progression and metastasis (Yun et al., 2020)."
35846989
reach
"Overexpression of USP21 increase the cell growth, invasion and cancer stem cell percentage of 786-O and A-704 cells."
27259257
reach
"To further show the importance of this protein in cellular invasion, knockdown of USP25 significantly reduced cell invasion and its overexpression increased cell invasion as assayed by transwell invasion assays."
25762624
reach
"XREF_BIBR, XREF_BIBR Recently, one report indicated that USP21 promotes cell proliferation and invasion ability in human renal cell carcinoma."
28223825
reach
"USP21 can promote tumorigenesis by increasing the cell proliferation, migration, and invasion of non-small cell carcinoma cells ."
37714937
reach
"USP25 promotes HCC cell proliferation, migration, and invasion in vitro ."
37439386
reach
"Collectively, these results demonstrated that USP25 promotes HCC cell proliferation, migration, and invasion."
37439386
reach
"USP21 promotes migration and invasion ability of BC cells and facilitates EMT."
28223825
reach
"We reported that USP21 promoted GC cell proliferation, migration, invasion, and stemness in vitro, and regulated GC tumor growth and cell stemness in mice in vivo."
33791299
reach
"In non small cell lung cancer, USP21 promotes tumor cell proliferation, migration, and invasion through the YY1 and SNHG16 axis."
33791299
reach
"The expression of USP21 may promote proliferation, migration and invasion of breast cancer cells."
28105162
reach
"USP21 Promotes the Proliferation, Migration, Invasion, and Stemness of GC Cells."
33791299
reach
"Afterward, the role of USP21 in cell migration and invasion was evaluated through Transwell assay, and the data in XREF_FIG showed that overexpression of USP21 accelerated the migration and invasion of AGS cells, whereas knockdown of USP21 pronouncedly reduced the migration and invasion of MKN-45 cells."
33791299
reach
"These results demonstrated that USP21 stimulated cell proliferation, migration, invasion, and stemness of GC cells."
33791299
reach
"Subsequently, according to a series of experiments, we observed that overexpression of USP25 promoted HCC cell proliferation, migration, and invasion both in vitro and in vivo; in particular, HCC cells noticeably spread to the lungs."
37439386
reach
"USP21 promotes NSCLC migration and invasion."
31956270
reach
"Ding et al. revealed that miR–27a–3p-induced USP25 suppression inhibited EMT, migration, and invasion of trophoblastic cells in RPL [16]."
34654357
reach
"USP21 overexpression significantly promoted cell migration and invasion, whereas USP21 silencing inhibited cell migration and invasion (Fig. 3a)."
31956270
reach
"Knockdown of USP21 inhibited the Migration and Invasion of Nasopharyngeal Carcinoma Cells."
36820242
reach
"Thus far, a study proved that USP21 can accelerate cell growth, invasion, and stemness of renal cell carcinoma."
33791299
reach
"These results proved that knockdown of USP21 inhibited the migration and invasion of nasopharyngeal carcinoma cells."
36820242
reach
"Silencing of USP25 was shown to inhibit invasion and metastasis of human non-small cell lung cancer [52]."
30527624
reach
"The results from these assays indicated that USP25 promotes HCC cell proliferation, migration, and invasion by interacting with TRIM21, thereby regulating the Wnt/β-catenin signaling pathway and EMT [Figure 8]."
37439386
reach
"We also showed that USP21 contributed to the progression of tumorigenesis by increasing proliferation, migration, and invasion."
31956270
reach
"However, another study reported that USP21 promotes non-small cell lung cancer (NSCLC) cell proliferation, migration, and invasion, including A549 cells, by deubiquitinating and stabilizing an oncoprotein, Yin Yang-1 (YY1) [43]."
37743467
reach
"USP21 silencing inhibited proliferation, migration and invasion and induced apoptosis of HCC cells, accompanied by the increased E-cadherin protein expression and decreased N-cadherin and Vimentin protein expression."
39680331
reach
"In non-small cell lung cancer, USP21 promotes tumor cell proliferation, invasion and migration through the YY1/small nucleolar RNA host gene 16 pathway (97)."
40230426
reach
"USP21 inhibition suppressed AMC-HN-8 and TU686 cell proliferation, migration and invasion."
36919585