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USP13 inhibits ACLY. 2 / 2

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"These data suggest that USP13-KD induces mitochondrial dysfunction and lipogenic dysfunction by reducing OGDH and ACLY activity, thereby reducing glutamine 's reductive carboxylation and glucose 's oxidation for lipid synthesis (XREF_FIG)."

27892457

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"Depletion of USP13 markedly decreased protein stability of ACLY and OGDH (XREF_FIG; XREF_SUPPLEMENTARY), but had no effect on the transcription of ACLY and OGDH (XREF_FIG)."

27892457

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IndraLab

Statements

USP13 inhibits ACLY. 2 / 2

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