IndraLab
Statements
Notch signaling pathway activates OTUD7B. 1 / 1
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"In addition, both the RHBDL2-SA and RHBDL2 plus OTUD7B-silencing groups significantly reversed the increased expression levels of the Notch signaling pathway downstream target genes (HES1, HEY1, ZEB1, MMP9, SNAIL1, and TWIST1) and cleaved Notch1 (Fig. 7F, G), as well as the enhanced luciferase reporter activity (Fig. 7H) mediated by the RHBDL2."