IndraLab

Statements

BRAF activates USP5. 3 / 3
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"Overall, our results demonstrate that BRAF activates Usp5 to suppress cell cycle checkpoint control and apoptosis by blocking p53 and FAS induction; all of which can be restored by small molecule-mediated Usp5 inhibition."
24980819
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"Usp5 was consistently suppressed, but not fully inhibited, by kinase inhibitor or BRAF knockdown."
24980819
reach
"Overall, our results demonstrate that BRAF activates Usp5 to suppress cell cycle checkpoint control and apoptosis by blocking p53 and FAS induction; all of which can be restored by small molecule mediated Usp5 inhibition."
24980819