IndraLab

Statements

Histone inhibits RELA. 2 / 2
| 2
reach
"Based on these combined results, it appears that acetylation is required for maximal activity of p65, which is consistent with results showing that overexpression of CBP and p300 enhances the activation potential of p65, whereas overexpression of histone deacetylases (HDAC) represses p65 activity."
28334776
reach
"We previously reported that the epigenetic signature requires induction of NF-kappaB factor RelB, which directs histone H3K9 dimethylation, disrupts assembly of transcription activator NF-kappaB p65, and induces a sustained switch from the euchromatin to heterochromatin."
19158276