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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP25 activates homologous recombination. 3 / 3

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"Deactivation of USP21 reduces the HR activity and increases the DNA damage frequency [XREF_BIBR]."

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"Cells overexpressing USP21 increased HR efficiency, and cells defective of USP21 showed a significant decrease in HR [33]."

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"Notably, tumor associated SCNAs often result from non allelic homologous recombination events 49, consistent with our observation that USP21 positively regulates HR."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP25 activates homologous recombination. 3 / 3

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