IndraLab

Statements

ALKBH5 activates USP22. 3 / 3
| 1 2
reach
"ALKBH5 mediates its protumorigenic function by inducing the stability of histone deubiquitinase ubiquitin specific peptidase 22 (USP22) and ubiquitin ligase RING finger protein 40 (RNF40) in a RNA methylation-dependent manner."
35303054
eidos
"Significance : RNA demethylase ALKBH5 upregulates USP22 and RNF40 to inhibit histone H2A ubiquitination and induces expression of key replication and DNA repair-associated genes , driving osteosarcoma progression ."
35303054
reach
"In one study, the protumorigenic function of ALKBH5 was mediated by regulating m6A of histone deubiquitination ubiquitin-specific peptidase 22 (USP22) and ubiquitin ligase RING finger protein 40 (RNF40)."
37766615