IndraLab

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OTUD1 binds polyubiquitin chains. 2 / 2
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"We also found that the deubiquitinase OTUD1 directly interacts with CARD9 and cleaved polyubiquitin chains from CARD9, leading to the activation of the canonical NF-κB and MAPK pathways."

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"OTUD1 directly interacted with CARD9 and cleaved polyubiquitin chains from CARD9, leading to the activation of the canonical NF-kappaB and MAPK pathway."