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Statements

BRCC3 decreases the amount of BRCC3. 3 / 4
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"Consistently, BRCC3 siRNA treatment of MDA-MB 231 cells caused decreased expression of BRCC3 and p-ERK."
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"Western blot analysis showed that interference with BRCC3 upregulated E-cadherin protein expression and downregulated BRCC3, ZEB1 and vimentin protein expressions, and overexpression of ZEB1 reversed these effects ( Figure 4F)."
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"Here, we showed that most RNF213- and BRCC3 associated miRNAs were elevated in serum of MMD patients, repressed RNF213 and BRCC3 protein expression in HBMVEC, and modulated HBMVEC angiogenesis."
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