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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

HCN1 activates 3',5'-cyclic AMP. 2 / 2

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"However, this simple view is not supported by our finding that, in cell-free patches, the response of HCN1 channels to direct application of cAMP is unaffected by coexpression TRIP8b."

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"This, in turn, was associated with a significant reduction of the dendritic hyperpolarization activated cyclic AMP gated channel type 1 (HCN1) protein level while Kv4.2 channels were unaltered as assessed by western blot."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...