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Capsaicin inhibits FOS. 2 / 2
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"Elevated c-fos activity leads to excessive activation of the cardiac SNS and adverse cardiac outcomes.36 37 In this study, CAP administration significantly reduced c-fos activity in both the PVN and SCG, indicating restrained cardiac SNS overactivation."
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"Therefore, these neuronal profiles appear to have been elicited by noxious stimulation with capsaicin to the tongue, which is mainly innervated by the LIN.After injury to the LIN, a decreased number of capsaicin-induced c-Fos immunolabeled neuronal profiles was noted in the ipsilateral Vc, but that on the contralateral side remained unchanged."
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