IndraLab

Statements

USP8 binds ESR1. 4 / 4
2 | 2
sparser
"Overall, our findings suggest that DC-U4106 is a promising drug candidate and targeting the USP8-ERα complex could be a new approach to treat ER-positive or drug-resistant breast cancer."
35786929
biogrid
No evidence text available
35786929
sparser
"Dysregulation of ERα drives cancer initiation and progression [ xref ], and USP8 interacts with ERα to enhance its protein stability—this, in turn, increases ERα signaling activity and sustains the proliferative capacity of breast cancer cells [ xref ]."
41331709
biogrid
No evidence text available
35786929