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Statements


USP1 deubiquitinates IRF1. 1 / 1
1 |

"In addition, we found that downregulation of <span class="match term1">IRF1</span> is mediated by its degradation through the ubiquitination-proteasome pathway, and that decreased activity of a deubiquitinase complex containing <span class="match term0">USP1</span> and UAF1 is involved in the degradation of <span class="match term1">IRF1</span> by Wnt/beta-catenin signaling"