IndraLab

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USP8 binds EPG5. 11 / 11
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"The results showed that USP8 is immunoprecipitated by EPG5, indicating that there is an interaction between EPG5 and USP8 (Fig. 3b)."
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"Co-IP assay confirmed the interaction between EPG5 and USP8 in ESCs (Fig.  xref )."
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"Furthermore, immunofluorescence microscopy showed that EPG5 did directly interact with USP8 in ESCs (Fig.  xref )."
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"The results showed that USP8 is immunoprecipitated by EPG5, indicating that there is an interaction between EPG5 and USP8 (Fig.  xref )."
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"These data support that EPG5 binds to USP8."
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"These data support that EPG5 binds to USP8."
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"To examine whether USP8 binds to EPG5 in cells, we transfected Flag-tagged Epg5 and/or HA-tagged Usp8 in HEK293T cells and performed coimmunoprecipitation (co-IP) assays."
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"To examine whether USP8 binds to EPG5 in cells, we transfected Flag-tagged Epg5 and/or HA-tagged Usp8 in HEK293T cells and performed coimmunoprecipitation (co-IP) assays."
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"EPG5 directly interacts with USP8."
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"To further confirm that EPG5 interacts with USP8 in ESCs, stable ESC lines harboring HA- Epg5 or Myc- Usp8 vectors were established."
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"This work uncovers a novel crosstalk pathway between ubiquitination and autophagy through USP8-EPG5 interaction to regulate the stemness of ESCs."
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