IndraLab

Statements

KCNA3 activates cell population proliferation. 6 / 9
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"For example, it has been shown that Kv1.3 (KCNA3) and Kv3.1 (KCNC1) blockade increases neural progenitor cell proliferation [XREF_BIBR]; likewise, induction of H + flux induces regeneration of a complex appendage [XREF_BIBR] and blockade of gap junction mediated signals results in the formation of a complete, properly patterned head in a planarian tail blastema [XREF_BIBR]."
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"As we know, T cell activation and proliferation are initially regulated by Kv1.3 on the cell membrane."
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"Compared with control group, gene silencing of Kv1.3 and KCa3.1 respectively inhibited the proliferation of T cells."
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"Here, we show that Kv1.3 promotes the proliferation of preadipocytes through the control of mitochondrial dynamics."
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"Plasma membrane Kv1.3 mediates cellular activation and proliferation, whereas mitochondrial Kv1.3 participates in cell survival and apoptosis."
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"Our results demonstrate that Kv1.3 promotes preadipocyte proliferation and differentiation by controlling mitochondrial membrane potential and mitochondrial dynamics at the G1 phase of the cell cycle."
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