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BACE1 decreases the amount of UCHL1. 1 / 1

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" Aβ 42 mediated increase in BACE1 expression is accompanied by a decrease in Uch-L1 expression and activity in dif- ferent cellular models and in sporadic AD brains, which interferes with the lysosomal degradation of BACE1 [52,56]."

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BACE1 decreases the amount of UCHL1. 1 / 1

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