IndraLab

Statements

USP47 activates BCR-ABL. 4 / 4
| 4
reach
"We show that knockout of Usp47 significantly prevents BCR-ABL or BCR-ABL T315I -induced leukemogenesis and reduces the number of GFP + LSK cells in CML mice, indicating that Usp47 is critical in the development of BCR-ABL-induced CML."
33397955
reach
"USP47 knockdown significantly inhibited both BCR-ABL-induced CML in mice and BCR-ABL -induced CML, which are known to confer Imatinib and second-generation TKI resistance ."
37740002
reach
"USP47 knockout significantly inhibited BCR-ABL and BCR-ABL -induced mouse CML with reduced of LIN Sca1 c-kit CML stem cells/progenitor cells."
34604226
reach
"The knockout of Usp47 significantly inhibits BCR-ABL and BCR-ABL T315I -induced CML in mice with the reduction of Lin - Sca1 + c-Kit + CML stem and progenitor cells."
33397955