IndraLab

Statements

CACNA1A activates apoptotic process. 15 / 15
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"Mhp infection decreases host immunity and induces significant apoptosis or dysfunction to immune cells, as well as increasing the secondary viral or bacterial infection risk.With the development of modern swine production goes to larger-scale and intensive, coinfections of Mhp and other pathogens are becoming common and serious."
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"We presume that BI-TK and GCV treatment system is able to prevent tumor growth and induce apoptosis in the rodent bladder cancer model by down-regulating Prx-I expression."
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"Specific association of SCA6 pathology clearly implies that small CAG expansion of the CACNL1A4 gene disturbs normal functions of the alpha 1A Ca 2+ channel, and ultimately produce apoptosis of Purkin[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, HaCSTC overexpression protected VHSV-infected FHM cells against VHSV-induced apoptosis and increased cell viability."
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"The late-stage apoptosis induced by the Mhp strain JS or 168L in hTERT-PTECs was significantly decreased when rNFOR was blocked with an anti-rNFOR antibody."
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"Mhp can also induce immune cells apoptosis by ROS production, excessive NO release and caspase activation, and increases the risk of coinfection with other pathogens."
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"Whether early or late apoptosis, the proportion of cells induced by MHP was similar to that of radiation (5 Gy), while being greater than that of MH."
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"Thereafter, Mhp can adhere to the cilium surface and spread through the respiratory tract, destroying cilium structures and causing apoptosis to epithelial cells (60)."
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"Follow-up studies reported Mhp infection could induce apoptosis to PBMCs by ROS and NO production, which were related to the Bax/Bcl-2, p38 MAPK signaling pathway and caspase activation (93)."
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"The BI-TK and GCV system (group C) was shown to inhibit tumor growth and caused the apoptosis of tumor cells as assessed by in situ terminal transferase dUTP nick-end labeling assay."
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"FCM analyses of annexin-V, APCA, and PI revealed that lentivirus-mediated inhibition of CYLD significantly prevented early and total apoptosis (LR and TR, respectively) but not late apoptosis (UR) when compared with the sh-GFP groups (Fig. 5B; LR 4.98 ± 0.94 vs. 7.15 ± 0.10, P = 0.016; UR 1.65 ± 1.14 vs. 3.51 ± 1.19, P = 0.122; TR 6.63 ± 0.21 vs. 10.67 ± 1.28, P = 0.029)."
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"Mhp Can Induce Apoptosis to PAMs by Nitric Oxide and (ROS) Production."
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"Partial pattern diagram of Mhp infection is shown in Figure 2, Mhp infection destroys cilium structures and induces the apoptosis of epithelial cells, which may increase the risk of secondary infections."
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"The BI-TK and GCV treatment system exhibited a sustainable anti-tumor growth activity and induced apoptosis in bladder cancer tissues by inhibition of Prx-I through the NF-kappaB pathway."
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"The late-stage apoptosis induced by either the high-virulence Mhp strain JS or the low-virulence Mhp strain 168L in hTERT-PBECs was significantly decreased when rNFOR was blocked with an anti-rNFOR polyclonal antibody, with late-stage apoptotic cell percentages decreasing by 41.9 and 35.8%, respectively."
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