IndraLab

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USP13 activates PRPF6. 3 / 3
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"Our subsequent analyses revealed that USP13 enhanced the stability of PRPF6 by reducing its K48/63‐linked polyubiquitination level, a process mediated by the deubiquitinating activity of USP13."
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"These results suggest that overexpression of USP13 promotes the proliferation of HCC cells.3.4 USP13 Stabilises PRPF6 Protein by Decreasing Its K48/63-Linked Polyubiquitination Levels."
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"In contrast, USP13 overexpression markedly increased PRPF6 protein stability (Figure 5G)."
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