IndraLab

Statements

USP13 activates ERAD. 3 / 3
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reach
"Despite having opposing activities, USP13 can cooperate with gp78 to promote ERAD."
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eidos
"On the other hand , USP13 antagonizes AMFR by deubiquitinating UBL4A to maintain the integrity of BAG6 complex and therefore promotes ERAD ( Liu et al ., 2014 ) ."
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reach
"By contrast, USP13 depletion did not affect deglycosylation of TCRalpha (lane 2 vs 1), suggesting that USP13 promotes ERAD downstream of p97."
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