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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP6 phosphorylates STAT3. 3 / 3

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"As shown in xref , the pan-Jak inhibitor blocked USP6-induced phosphorylation of STAT3 in a dose-dependent manner, but had no effect on tyrosine phosphorylation induced by Src or the EGF receptor."

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"USP6-induced STAT3 phosphorylation was completely abrogated in cells depleted of Jak1 (USP6/J1#17)."

27440725

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"A pan-Jak inhibitor completely blocked USP6-induced phosphorylation of STAT3, while the pan-Src PP2 inhibitor was ineffectual ( xref )."

27440725

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USP6 phosphorylates STAT3. 3 / 3

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