IndraLab

Statements

USP15 activates inflammatory response. 5 / 5
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"Hepatocyte deletion of USP15 suppresses liver steatosis, inflammation, and fibrosis in mouse models of NASH."
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"Here we described that USP15 promotes proliferation and inflammation in keratinocytes by stabilizing squamous cell carcinoma antigen 2 (SCCA2)."
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"In addition, USP15 is necessary for the metastasis and inflammatory response in MDA-MB-231 BC cells induced by TGFβ-signaling [149]."
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"Researchers discovered that The expression of the deubiquitinating enzyme USP15 is upregulated in the livers of HFD-fed mice and in liver biopsy tissues from patients with NAFLD or NASH, whereas hepatocyte deletion of USP15 suppresses hepatic steatosis, inflammation, and fibrosis in a mouse model of NASH (133)."
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"Here we described that USP15 promotes proliferation and inflammation in keratinocytes by stabilizing squamous cell carcinoma antigen 2 ( SCCA2 ) ."
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