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BAP1 deubiquitinates H2AK119. 2 / 2

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"28 ASXL1 may also collaborate with BAP1, loss of which led to a myelodysplastic syndrome like syndrome in a mouse model, to deubiquitinate H2AK119 at polycomb group targets."

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"BAP1 is activated by ASXL1 and deubiquitylates mono-ubiquitylation of H2AK119 (Daou et al. 2015; Sahtoe et al. 2016)."

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BAP1 deubiquitinates H2AK119. 2 / 2

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