IndraLab

Statements


BAP1 binds GEP. 3 / 3
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"Inactivating mutations in the tumor suppressor BAP1 are associated with the class 2 GEP and high metastatic risk xref , whereas single nucleotide substitutions in SF3B1 and EIF1AX are found mainly in class 1 tumors and are associated with intermediate and low metastatic risk, respectively xref , xref ."

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"BAP1 mutations were associated with class 2 GEP ( P < ."

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"Mutations in SF3B1 and EIF1AX are associated with Class 1 GEP and have been reported to be good prognostic factors in UM, whereas BAP1 mutations are associated with Class 2 GEP and poor prognosis ( xref , xref )."