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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

UCHL1 activates HSPA5. 3 / 3

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"We found that GRP78 was significantly increased in CFs treated with UCHL1 siRNA, consistent with an investigation in SK-N-SH cells 35."

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"This study demonstrates that UCHL1 enhances cardiac fibrosis after MI by interacting with and downregulating GRP78 by ubiquitination."

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"We found that GRP78 was upregulated in TGF-beta1 stimulated CFs and a greater increase of GRP78 was observed in TGF-beta1 stimulated CFs treated with UCHL1 siRNA."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

UCHL1 activates HSPA5. 3 / 3

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