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USP18 inhibits JAK1-IFNAR2 interaction. 1 / 1

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"As a negative regulator of the Jak / STAT signaling , USP18 binds to the intracellular domain of IFNAR2 to block the JAK1-IFNAR2 interaction , leading to the inhibition of signal transduction ( Malakhova et al ., 2006 ) ."

34017322

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USP18 inhibits JAK1-IFNAR2 interaction. 1 / 1

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