IndraLab

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USP1 deubiquitinates TBK1. 4 / 4
| 4
reach
"Studiy have shown that in the antiviral response signaling pathway of type I interferon, the deubiquitinase USP1 interacts with TBK1 to deubiquitinate TBK1, enhance the expression of downstream type I interferon, and inhibits viral replication (Yu et al., 2017)."
35873150
reach
"USP1 greatly inhibited TBK1 ubiquitination, whereas USP12 and USP46 had no effects on TBK1 ubiquitination."
29138248
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"USP1 has been reported to enhance the activation of STAT1 (phosphorylation on tyrosine 701, pSTAT1) by deubiquitinating and stabilizing tank binding kinase 1 (TBK1) [34]."
37289831
reach
"Studies have shown that in the antiviral response signaling pathway of type I interferon, the deubiquitinase USP1 interacts with TBK1 to deubiquitinate TBK1, enhance the expression of downstream type I interferon, and inhibits viral replication (Yu et al., 2017)."
35873150