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APC_C ubiquitinates USP22. 2 / 2

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"Fourth, USP22 is ubiquitinated and degraded by CDC20 containing APC/C complex during cell exit from M phase, presumably to release the brake on CCNB1 degradation."

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"Lastly, ubiquitylation of USP22 mediated by the anaphase promoter complex and cyclosome (APC/C) induces USP22 protein degradation during the cell cycle [XREF_BIBR]."

27057639

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IndraLab

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APC_C ubiquitinates USP22. 2 / 2

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