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T-box increases the amount of HCN4. 1 / 1

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"HCN4 expression is specifically stimulated in SAN tissue by T-box 3 (Tbx3), a transcriptional repressor whose activation is essential for development of the SAN and atrioventricular node (AV) bundle and segregation of pacemaker SAN from atrial cell lineages; this correlation further supports the view that HCN4 is a SAN marker gene [XREF_BIBR]."

19361514

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IndraLab

Statements

T-box increases the amount of HCN4. 1 / 1

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