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USP37 decreases the amount of USP37. 2 / 2
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"Premature CMG unloading was suppressed by supplementing USP37-depleted extracts with wild-type HA-tagged USP37 (USP37 ; expressed in a transcription-translation extract), but not with catalytically inactive USP37 (USP37 ; Fig. 3b, lanes 2, 4, 6, 8; Extended Data Fig. 5f)."

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"After a correlation of OS and DFS was seen with the expression of USP37, we modulated the expression of USP37 by overexpression and depletion of USP37 to identify its molecular targets in osteosarcoma especially pertaining to replication stress."