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USP46 activates ENO1. 3 / 3
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"These results indicated that USP46 promotes ESCC cell metastasis through regulating ENO1.To further validate the relationship of USP46 and ENO1 in ESCC, we examined the expression of ENO1 in 48 clinic[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In addition to affecting the proliferation of cancer cells, USP46 has also been demonstrated to promote tumor metastasis by stabilizing ENO1 in human esophageal squamous cell carcinoma [ 28 ]."

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"Increased USP46 prolonged the half-life of ENO1 by antagonizing ENO1 ubiquitination and inhibiting ENO1 proteasome-associated degradation."