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USP28 deubiquitinates STAT3. 3 / 3
1 | 2

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"As shown in XREF_FIG, the IP indicated that STAT3 itself was polyubiquitinated and USP28 deubiquitinated the polyubiquitination of STAT3."

"Immunoprecipitation was performed to assess whether <span class="match term0">USP28</span> interacted with <span class="match term1">STAT3</span> or deubiquitinated <span class="match term1">STAT3</span>"

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"The deubiquitinating enzyme USP28 mediates STAT3 signaling in non-small-cell lung cancer cells, and USP28 interacts with STAT3 and enhances its stability by inducing the deubiquitination of STAT3 [22]."