IndraLab

Statements

MINDY1 decreases the amount of YAP1. 2 / 2
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"It was found that MINDY1 deletion dramatically decreased YAP protein level, and this effect could be reversed by addition of the proteasome inhibitor MG132 or overexpression of MINDY1-WT, but not its catalytically inactive mutant MINDY1 (Fig. 3A, B)."
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"Downregulation of MINDY1 disrupted the YAP stabilization and inhibited the expression of YAP downstream genes, such as CTGF, CYR61 and ANKRD1 in bladder cancer (88)."
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