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USP7 decreases the amount of CDKN1C. 3 / 3
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"We also found that USP7 knockdown in Bcpap cells significantly increased the expression of p57 KIP2 mRNA via qRT-PCR ( Fig. 3 b)."

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"As shown in the Western blotting results in Supplementary Fig. 4a, whereas USP7 overexpression suppressed p57 KIP2 expression, the upregulation of p57 KIP2 reversed the decline in p57 KIP2 expression [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Indeed, USP7 upregulation elevated the TBX3 protein levels and reduced p57 KIP2 protein expression in 8505c cells, as shown by Western blotting, and overexpression of USP7 decreased p57 KIP2 promoter [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"