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OTUD6B inhibits Triple Negative Breast Neoplasms. 2 / 2
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"In breast cancer, over-expression of OTUD6B‐AS1 has been found to promote autophagy and thus genomic instability via the lncRNA OTUD6B-AS1/miR-26a-5p/MTDH signalling pathway, this lncRNA promotes the progression of triple-negative breast cancer 19."
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"In addition, in triple-negative breast cancer, OTUD6B can activate autophagy and DDR inhibition through the OTUD6BAS1/miR-26a-5p/MTDH axis, thereby mediating genomic instability and promoting the development of PTX drug resistance [18]."
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