IndraLab

Statements

Cholesterol inhibits CASP1. 2 / 2
| 2
reach
"Collectively, these results demonstrate that restoration of cholesterol levels during the second signal of inflammasome activation reduces inflammasome assembly, caspase-1 activation, and IL-1beta production in cells deficient in lipin-2."
28031477
reach
"The results indicated that MUC5AC secretion could be decreased in cultured cholesterol-exposed biliary cells through three ways: by inhibiting inflammasomes with siRNAs, inhibiting IL-1 receptor, or inhibiting caspase-1 with Ac-YVAD."
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