IndraLab

Statements

USP42 binds TP53. 7 / 12
3 | 3 4
sparser
"USP42 forms a direct complex with p53 and controls level of ubiquitination during the early phase of the response to a range of stress signals including Dox [ xref ].."
24143256
sparser
"USP42 forms a direct complex with p53 and controls level of ubiquitination during the early phase of the response to a range of stress signals."
22085928
sparser
"Usp42 forms a direct complex with p53 and controls its activation in response to cellular stress; as a result it regulates p53-dependent transcription and cell cycle arrest."
25962961
reach
"It has been reported that USP42 interacts with and deubiquitinates p53."
24143256
reach
"In animal, USP7, USP10 and USP42 bind to and deubiquitylate the substrate p53 to counteract its degradation ."
31745110
sparser
"USP42 interacts with p53 and dominates p53 ubiquitination in response to stress signals such as Dox [22] ."
28807825
reach
"When subjected to external pressure, ubiquitin-specific peptidase 42 (USP42) can bind to p53 and stabilize its protein by removing the ubiquitin chain."
36613989