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USP8 activates Stomach Neoplasms. 3 / 3
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"These results indicated that down-regulation of USP8 could promote the apoptosis of HER3 positive GC cells and inhibit the proliferation of them by affecting the cell-cycle."
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"So, it can be assumed that the inhibition or silencing of USP8 may prevent the growth of GC cells as well as metastasis through the inhibition of this PI3K/AKT signaling pathway which is needed to pro[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Moreover, down-regulation of USP8 could promote the apoptosis of HER3 positive GC cells and inhibit the proliferation of them by affecting the cell-cycle."
32848421